If Mr. House does show up in 2296 when Season 2 is set then that would seem to settle the fan debate over which ending of Fallout: New Vegas is canon. In the game, a victory for Mr. House is one where he survives the Battle of Hoover Dam, pushes out the other factions, and remains in control of Vegas.

The 'Fallout' Season 2 trailer reveals that Justin Theroux is Robert House, plus there's a deathclaw in New Vegas.

Aside from Purnell, Goggins, and McLachlan, season two will see Aaron Moten’s return as Maximus—the wayward Brotherhood of Steel soldier who was tragically separated from Lucy after their close bond in season one—alongside Moisés Arias as Norm, Lucy’s brother who managed to uncover the secret of the Vaults himself at the climax of last season.