The proton gradients that power respiration are as universal as the genetic code itself, giving an insight into the origin of life and the singular origin of complexity. Why do virtually all cells ...

The way a key cellular motor works at an atomic level has been uncovered by simulations conducted by RIKEN biophysicists.

Using electron microscopy and high-speed atomic force microscopy, researchers show the internal molecular motor behind the gliding mechanism for Mycoplasma mobile to consist of two ATP synthase-like ...

"The ATP synthase protein complex consists of a spinning rotor driven by the back transport of protons into the mitochondrial matrix. This part is connected to the enzyme's catalytic head by a stalk, ...

Each year, about 1,000 to 4,000 children in the United States are born with a mitochondrial disease. Many of these diseases are tied to a deficiency in ATP synthase thought to be triggered by ...

ATP is produced by an enzyme called ATPase, which consists of two molecular motors, F o and F 1, that rotate in opposite ...

F-Type ATP synthase, a catalytic complex of proteins, synthesizes adenosine triphosphate (ATP), the energy currency of living cells. A lot of ambiguity exists over the rotational mechanism of this ...

Mitochondrial ATP synthases form dimers, which assemble into long ribbons at the rims of the inner membrane cristae. We reconstituted detergent-purified mitochondrial ATP synthase dimers from the ...

Mitochondrial dysfunction, including decreased mitochondrial respiration and increased mitochondrial stress, is associated with many major human diseases and casual to many pathological defects.

Recently, a research team led by Professor Hongzhe SUN from the Department of Chemistry, Faculty of Science, The University of Hong Kong, has published a paper in Nature Communications. The ...

For more than 20 years, Makoto Miyata from Osaka City University has been studying the gliding motility of the parasitic bacterium Mycoplasma mobile (M. mobile). It is a mechanism consisting of an ...