Actin, traditionally associated with the cytoskeleton, also assembles within the nucleus in response to developmental cues, stress and signalling pathways. Nuclear actin exists in monomeric (G-actin) ...

A tiny chemical modification on one of the most abundant and important proteins in cells, actin, has long been somewhat mysterious, its function not fully understood, but scientists have now taken a ...

Over the last several years the identification and functional characterization of the motor proteins actin and myosin in the nucleus has initiated a change in the view of nuclear processes. It is now ...

Historically, actin research at different levels of biological organization has developed into separate fields such as in vitro actin biochemistry, biophysics and cell biology. Biochemists, cell ...

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...

Tiny things matter – for instance, one amino acid can completely alter the architecture of the cell. Researchers at the Universities of Göttingen and Warwick investigated the structure and mechanics ...

Cells are characterized to be stable yet highly flexible. They constantly modify their shape and even move through tissue. These vital properties are based on a dynamically organized network of ...

Cells use the polymerization of actin alone to create some types of movement, but many other forms of movement require interplay between actin and an enzyme called ...