Intuniv is available as 1mg, 2mg, 3mg, and 4mg extended-release tablets The Food and Drug Administration (FDA) has approved a new update to the Intuniv (guanfacine; Shire) labeling regarding ...
Induction of cytochrome P450 (CYP) by drugs is one of major concerns for drug-drug interactions. Thus, the assessment of CYP induction by novel compounds is a vital component in the drug discovery and ...
Efficacy and safety of obinutuzumab in the frontline treatment of CLL patients with comorbidities: The real-world results of Polish Adult Leukemia Group (PALG) retrospective analysis. This is an ASCO ...
Voxelotor 300mg; tabs for oral susp; grape flavor. Voxelotor is a hemoglobin S (HbS) polymerization inhibitor that binds to HbS and exhibits preferential partitioning to red blood cells. By increasing ...
May 12, 2004 — Substantial increases in trazodone hydrochloride (Desyrel) plasma concentration may occur with concurrent dosing of the cytochrome P450 3A4 (CYP3A4) inhibitors ketoconazole, ritonavir, ...
To examine whether CYP3A4 overexpression influences the metabolism of anticancer agent imidazoacridinone C-1311 in CHO cells and the responses of the cells to C-1311. Wild type CHO cells (CHO-WT), CHO ...
Switching from atorvastatin to another statin that is not metabolized by the CYP3A4 pathway can decrease platelet reactivity among patients after percutaneous coronary intervention (PCI) who respond ...
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. Serious ...