Clonidine is typically prescribed for managing blood pressure, but it’s also been used off-label for decades to ease opioid withdrawal symptoms. Opioid withdrawal symptoms can be extremely ...
In critically ill patients, sedation with alpha-2 adrenergic receptor agonists such as dexmedetomidine and clonidine, introduced within 48 hours of initiating mechanical ventilation, was not superior ...
Intraoperative bleeding volume was 1,088.7 cc in the clonidine group compared with 1,420.9 cc in the placebo group (P<0.001), and 6.8% of patients required blood transfusion compared with 22.7%, ...
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