Cancer research, drug safety testing and ageing biology may all gain a major boost from a new fluorescent sensor developed at ...

A breakthrough live-cell sensor makes DNA repair visible as it happens, unlocking new possibilities in biology and medicine.

DNA lesions are repaired by a cut-and-remove process called nucleotide excision repair. An in vitro biochemically defined system has been developed in which six repair factors are sufficient to excise ...

The gene editing tool known as CRISPR-Cas9 is changing what's possible for treating a wide range of diseases caused by ...

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...

DNA-PK can help repair DNA double-stranded breaks in one of two ways. For breaks with missing information, it can target enzymes that can fill in missing nucleotides — sort of like a needle and thread ...

Artios Pharma, which looking for newer targets that, like PARP inhibitors, affect the way tumors fix themselves, said its ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

(Nanowerk News) A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA. Such mistakes are frequent in code-copying process in ...