Scientists have identified a key protein that helps tumors evade attacks by the immune system, contributing to poor responses to immunotherapy in the clinic. Immunotherapy is a cutting-edge approach ...
An antisense therapy restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome. This breakthrough was possible because of the novel findings, also presented ...
Collaboration with UMass Chan Medical School confirmed FMR1-217 as well as an RNA-targeted mechanism to restore functional FMRP protein to develop potential treatments for FXS QurAlis’ preliminary ...
Fragile X syndrome is a leading genetic cause of autism, as roughly one in three individuals with the syndrome also have autism. Moreover, mutations in the gene that causes fragile X syndrome, FMR1, ...
Investigators at the École Polytechnique Fédérale de Lausanne (EPFL; Swiss Federal Institute of Technology Lausanne) have identified a broad role for the fragile X mental retardation protein (FMRP) in ...
(Philadelphia, PA) – The process of turning genes into protein makes the insides of cells terribly crowded and complicated places. Signals tell machinery to transcribe the DNA of genes into messenger ...
What happens inside neurons when we memorize a password or learn the cello? Some of our basic understanding about learning and memory comes from the study of conditions in which cognitive development ...
The ability of synapses to strengthen or weaken, form anew, or disappear entirely underlies the brain’s capacity to establish functional neuronal circuits during development and to learn and remember ...
Immunotherapy is a cutting-edge approach to treating cancer by turning the patient’s own immune system against their tumor. Our increasing knowledge of the mechanisms by which the body regulates ...
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