HotSpot Therapeutics, Inc., a biotechnology company pioneering the discovery and development of oral, allosteric small ...

BOSTON, March 4, 2026 /PRNewswire/ -- HotSpot Therapeutics, Inc., a biotechnology company pioneering the discovery and development of oral, allosteric small molecules that target natural regulatory ...

Interferon regulatory factor 5 (IRF5) is a key transcription factor involved in the control of the expression of proinflammatory cytokine and responses to infection, but its role in regulating ...

This news release is available in French. Metabolic complications of obesity and overweight, such as type 2 diabetes, are an important challenge to public health. Teams led by Nicolas Venteclef, ...

Introduction: The interferon regulatory factor 5 (IRF5) gene is implicated in the toll-like receptor signaling pathway and has proinflammatory and chemotactic effects, but its role in the pathogenesis ...

Interferon regulatory factor 5 (IRF5) is a transcription factor activated downstream of Toll-like receptors (TLRs) 7, 8 and 9, and is predominantly expressed in dendritic cells, B cells, monocytes and ...

Scientists have identified a protein that acts as a "master switch" in certain white blood cells, determining whether they promote or inhibit inflammation. The study could help researchers look for ...