Pathological fractures occur in bone that lacks normal biochemical and viscoelastic properties. A few conditions are involved in the aetiology of fractures during infancy. Accurate and careful ...

A recent report details the first reported case of an osteolytic lesion in polycythemia vera and reviews current literature on osteolytic lesions in myeloproliferative neoplasms (MPNs) overall.

If you have multiple myeloma, cancerous plasma cells divide and grow inside your bone marrow. Plasma cells are white blood cells that make antibodies. They're part of your immune system. In multiple ...

Lytic bone disease is a major feature of multiple myeloma: 70% to 80% of patients have osteolytic lesions at diagnosis, and up to 90% develop lytic lesions during the course of their disease. 1 The ...

We describe a patient with an autoinflammatory disease in which the main clinical features are pustular rash, marked osteopenia, lytic bone lesions, respiratory insufficiency, and thrombosis. Genetic ...

Seven cases (9.8%) had positive radiographs (group I). The remaining 64 cases had negative radiographs (group II). Using the Student t test, no significant differences in average age, weight, or time ...

A 17-year-old girl presented to a hospital orthopedics department in Vietnam due to pain in her left hip joint, which she noted had been getting worse over the past month. Neither her personal nor her ...

Dr. John H. Stone: A 45-year-old woman was referred to the rheumatology clinic of this hospital because of retroperitoneal fibrosis and the possibility of IgG4-related disease. Seven years before the ...

A 35-year-old woman reported having a painful right shoulder of 4 months' duration. Physical examination showed shoulder stability and full arch motion. Plain radiographs at that time showed a large ...

Randomized, Placebo-Controlled, Phase II Study of Sequential Erlotinib and Chemotherapy As First-Line Treatment for Advanced Non–Small-Cell Lung Cancer We evaluated 62 consecutive patients undergoing ...

Multiple myeloma causes lytic or osteolytic lesions, which are areas of damage caused by cancerous plasma cells blocking natural bone growth. These lesions appear as small holes on X-rays. They often ...