MHC class II molecules are central to the adaptive immune response, serving as the means by which antigen-presenting cells, notably dendritic cells, display processed peptides to CD4+ T cells. This ...
The major histocompatibility complex class I (MHC-I) antigen presentation pathway is central to the adaptive immune response. In this process, intracellular proteins are degraded primarily by the ...
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Enhancing the cancer-immunity cycle through innovative vaccines
Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 5 (February 1, 2022), pp. 1-3 (3 pages) C. Liu, Y. Zhang, C. C. Liu, D ...
A large-scale MIT screen of tuberculosis proteins revealed several possible antigens that could be developed as a new vaccine for TB, the world’s deadliest infectious disease.
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