The hunt for antivirals has reached an unprecedented pace in light of the coronavirus 2019 (COVID-19) pandemic. The causal agent for this disease – severe acute respiratory syndrome coronavirus 2 ...

Transfection methods for gene regulation were widely investigated after the discovery of RNAi. 16 The DNA nanotechnology concept has shown promising results for the transfection of siRNA and antisense ...

A morpholino is a synthetic oligomer molecule that contains DNA bases on a methylene morpholine backbone, hence the naming convention: morpholine oligomer. Image Credit: Phonlamai ...

At the IDWeek 2023 infectious disease conference, Rachelle Koch, a medical student from the University of Texas Southwestern Medical Center, presented the work done in David Greenberg’s Lab on a new ...

In vivo morpholino oligomers targeting the 3′ untranslated region show efficacy against dengue virus Jan. 3, 2025 ...

Indiana University School of Medicine scientists have developed a new method that shifts the behavior of immunosuppressive cells in tumors, turning them from cancer protectors into tumor fighters.