ascopubs.org

Comprehensive Single Nucleotide Polymorphism Study Supports the Role of MDM2 in p53-Competent Chronic Lymphocytic Leukemia

In this issue, Gryshchenko et al 1 report that a known single nucleotide polymorphism (SNP) in the promoter region of MDM2 is associated with treatment-free and overall survival in chronic lymphocytic ...
Nature

Glutathione S-transferase gene polymorphisms (GSTM1, GSTT1, GSTP1) and prostate cancer: a case-control study in Tehran, Iran

In a case-control study, a total of 168 patients with histologically confirmed prostate adenocarcinoma (PCa) (age range, 48–85 years; mean 63.1±13.7), and a control group consisting of 336 volunteers ...
The New England Journal of Medicine

Toll-like Receptor 4 Polymorphisms and Aspergillosis in Stem-Cell Transplantation

Toll-like receptors (TLRs) are essential components of the immune response to fungal pathogens. We examined the role of TLR polymorphisms in conferring a risk of invasive aspergillosis among ...
ascopubs.org

UGT1A1 gene polymorphisms and clinical outcomes in small cell lung cancer (SCLC) patients treated with irinotecan-platinum chemotherapy: The first study from north India.

Phase I study of amrubicin and cisplatin with concurrent thoracic radiotherapy (TRT) in limited-disease small cell lung cancer (LD-SCLC). This is an ASCO Meeting Abstract from the 2017 ASCO Annual ...
The Scientist

The SNP Timeline

1982 The Human Polymorphism Study Center, the first academic institution to propose the systematic study of polymorphisms, is founded in Paris. Its primary objective: to make an inventory of all ...