RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions (IDR), reports a new study from the Institute of Science, Tokyo, Japan. Using ...

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

In recent decades, significant advances in science and technology have greatly enhanced understanding of the many biological molecules that contribute to life’s complexity. RNA is one such molecule ...

The molecular machinery that normally builds proteins inside cells has now taken on a new role as a "switch." A research team at POSTECH (Pohang University of Science and Technology) has developed a ...

Neurons face an exceptional proteostasis challenge because their extreme polarization requires rapid proteome remodeling at ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

The National Initiative for RNA Biology and its Applications (NIRBA) officially opened its new Hub at the National University ...

The Human Genome Project (HGP) ultimately revealed a DNA sequence of 3 billion base pairs known as the human genome, 1 spurring an enormous technological advance in scientific research and the ...