Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the kidneys. Over time, the ...

PKD is mainly caused by mutations in the PKD1 and PKD2 genes, affecting polycystin proteins. Disrupted signaling pathways, like cAMP and vasopressin, are major drivers of cyst growth. Tolvaptan is ...

Polycystic kidney disease (PKD) causes round, fluid-filled sacs called cysts to grow in your kidneys. These cysts can cause your kidneys to enlarge and function poorly. People with PKD can also ...

Polycystic kidney disease (PKD) is a genetic disorder marked by the growth of many fluid-filled sacs (cysts) in your kidneys. These cysts can grow to replace normal kidney tissue over time, leading to ...

MIT researchers including Robert Croy (left) and Bogdan Fedeles have discovered that a drug they originally developed as a potential cancer treatment may also hold promise in treating autosomal ...

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function. The disease affects more than 12 ...

Kidney cancer is moderately common, the sixth-most prevalent cancer diagnosis for men and women. Benjamin L. Maughan, MD, PharmD, assistant professor in the division of medical oncology, answers ...

Credit: Getty Images The inaugural ADPKD guideline introduces new ADPKD nomenclature and offers updated recommendations on therapies to slow disease progression. The inaugural ADPKD guideline from ...

On the list of medical terms we'd rather never hear, cancer is at the top. But when it comes to fighting it, knowledge is ...

Kidney cancer often develops without clear warning signs, making everyday risk factors more important than most people ...