Researchers at Johns Hopkins University have discovered a new cellular mechanism behind how humans ...

Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10 ...

DUBLIN--(BUSINESS WIRE)--The "Retinoic acid receptor agonists - Pipeline Insight, 2022" drug pipelines has been added to ResearchAndMarkets.com's offering. The report serves as an exhaustive source of ...

Human pluripotent stem cells (hPSCs), when exposed to the right molecular signals in the right order, can become any cell type in the human body. Regenerative medicine seeks to derive blood-forming ...

Vitamin A, or retinol, is produced from carotenoids in the livers of animals. It is also broadly defined as a series of compounds that have structures similar to retinol. It is essential for growth ...

The initial results of the APL0406 trial showed that the combination of all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO) is at least not inferior to standard ATRA and chemotherapy (CHT) in ...

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...