This article examines how exercise-induced exerkines prevent disease, as well as promote metabolic, cardiovascular, immune, ...

Can eating fat be good for us? Some fatty acid molecules actually play a crucial role in maintaining our health and cellular functions. By the early twentieth century, scientists and doctors widely ...

Cornell researchers have uncovered a built-in molecular "gate" that controls the production of the molecule nitric oxide, a crucial signaling molecule throughout biology that in humans helps regulate ...

A unique quality of the immune system is that it can generate a ‘memory’ response. This is generally referred to as ‘immune ...

Ketone bodies are not just about energy. These metabolites are powerful signaling molecules that have profound effects on the proteome and protein quality control in the brain. Scientists, working in ...

A UCLA study found that macrophages rely on interferon gamma signaling from past infections to preserve innate defenses.

(a) Disease progression can be classified into three states: the normal stage, pre-disease stage and disease stage, with the pre-disease stage representing a critical threshold just before the onset ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

SIRPα immunotherapy include targeting overexpressed CD47 in cancers to boost macrophage activity, using dual function molecules to enhance efficacy, and innovative drug designs reducing red blood cell ...

Neuroinflammation drives the progression of neurodegenerative disorders like Alzheimer's, Parkinson's, and multiple sclerosis ...