NK cells have a crucial role in cancer surveillance and offer a potential avenue for adoptive cell transfer as either mono- or combination immunotherapy. Previous investigations into transferring ...

A new UCLA Health Jonsson Comprehensive Cancer Center study suggests that the way immune cells are organized inside melanoma ...

Researchers have developed a non-chemotherapy treatment regimen that is achieving full remissions for some people with aggressive B-cell lymphoma that has come back or is no longer responding to ...

A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely ...

COPENHAGEN, Denmark--(BUSINESS WIRE)--Genmab A/S (Nasdaq: GMAB) today announced new results from the Phase 1b/2 EPCORE ® NHL-2 trial Arm 10 (NCT04663347), evaluating epcoritamab, a T-cell engaging ...

A subgroup analysis of a phase Ib/II trial showed durable responses with mosunetuzumab (Lunsumio) plus polatuzumab vedotin (Polivy) in transplant-ineligible large B-cell lymphoma patients in early ...

The standard treatment for patients with multiple myeloma often includes stem cell transplantation in which the patient's own stem cells are harvested and stored while the patient receives intensive ...

Scientists discovered which tumor cells resist treatment and why. By characterizing B-cells' developmental stages, they designed and tested a drug combination to effectively treat resistant B-cell ...

- Preclinical data identify SHP-1 as a downstream effector of GDF-15-mediated inhibition of T cell adhesion, further elucidating mechanistic details of GDF-15’s role in immunotherapy resistance. - ...