Ewing sarcoma (ES) and its variants are rare and aggressive malignancies, occurring in paediatric and younger adult populations. Adamantinoma-like ES (ALES) is one of its variants, characterised by ...

We present a case of human epidermal growth factor receptor 2 (HER2)-overexpressing, alpha-fetoprotein (AFP)-producing metastatic gastric adenocarcinoma diagnosed in the USA. Both HER2 overexpression ...

Cervical spine clearance in trauma patients is frequently guided by strict protocols, particularly when patients present with midline cervical tenderness or cannot be reliably examined. Although a ...

Abdominal aortic aneurysm (AAA) is an extremely rare condition in paediatric patients but can occur more frequently in patients with congenital connective tissue diseases such as Marfan syndrome or ...

Headaches in pregnancy are a common occurrence, and most differentials are benign but cerebral venous thrombosis (CVT) is a life-threatening secondary headache that is more common in pregnancy and ...

This report documents a young female patient with microgranular variant acute promyelocytic leukaemia (APL) harbouring FLT3-ITD mutation who presented with fatigue, fever, gum bleeding and altered ...

Radionecrosis describes a rare but serious complication of radiation therapy. In clinical practice, stereotactic radiosurgery (SRS) is increasingly used in combination with systemic therapy, including ...

A man in his 70s in a rehabilitation hospital, post cerebral infarct, became acutely short of breath with reduced oxygen saturations and an elevated d-dimer. Non-occlusive filling defects were noted ...

Scrotal haematoma is an extremely rare complication after cardiac catheterisation (CC) with only few cases reported in literature. We report a 56-year-old patient who developed large scrotal haematoma ...

A man in his 70s presented to hospital with an acute kidney injury. He recently had started taking valacyclovir for treatment of shingles. The valacyclovir was stopped and his acute kidney injury ...

Haemophagocytic lymphohistiocytosis (HLH) is a rare condition of uncontrolled immune activation as a result of an inherited genetic defect or in response to malignancy, autoimmune disease, ...

Sciatic hernia is a rare pelvic floor hernia. A variety of treatment modalities were proposed, but a guideline is lacking although a mesh-based tension-free repair may be preferred. A 67-year-old ...