If the 49ers make the playoffs McCaffrey might start to feel the effects of the 400-plus touches he’s on pace for, but that’s ...

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

Just one year after a massive contract extension, the 49ers and Brandon Aiyuk's relationship may be coming to an end.

He’s such an irreplaceable figure in the locker room and one of, if not the greatest tight end ever to wear the red and gold.

The San Francisco 49ers are back at Levi’s Stadium in Week 12 of the NFL season with a “Monday Night Football” matchup set ...

Christian McCaffrey enjoyed a big night after helping the San Francisco 49ers to a 20-9 victory over his former team, the ...

As both teams jockey for position in the playoff standings, the San Francsico 49ers battle the Carolina Panthers on Monday ...

The San Francisco 49ers entered Sunday in Week 11 with a healthy team, at least in terms of players on the roster.

Carolina is coming off an unusual offensive game wherein it did not run the ball particularly well but absolutely exploded in ...

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

"We do it all the time in practice, so it's not a big deal," Trent Williams said of McCaffrey's untouched TD. "But yeah, it's ...

Despite a challenging season with five losses, the Carolina Panthers, led by quarterback Bryce Young, are set to face the formidable San Francisco 49e ...