Get the best Panthers vs. 49ers predictions and odds ahead of their Monday Night Football clash at Levi's Stadium. Free NFL picks for November 24.

Monday Night Football in Week 12 of the NFL season features two potential playoff teams in the NFC in the Carolina Panthers and San Francisco 49ers. While many

Three first-half interceptions turned Purdy into a dink-and-dunker for the rest of the game. The 49ers need the good Purdy back pronto.

Monday Night Football brings us the resilient San Francisco 49ers -- a team that has overcome myriad injuries thus far -- hosting the feisty Carolina Panthers. McMillan has at least 60 yards in the two most recent appearances,

A ton of intriguing player prop targets face off on Monday night in Week 12 of the 2025 season, as the San Francisco 49ers host the Carolina Panthers in a huge

The 49ers won't get a chance to test themselves against the defending champs during the regular season, but could soon surpass them in the standings after the Eagles had a four-game winning streak snapped by a middling Dallas Cowboys team that rallied from a 21-point deficit.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 on a 48-33 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Our favorite Panthers vs. 49ers prop picks for Monday Night Football Week 12 are highlighted by star tight end George Kittle.

Shedeur Sanders has been named the starting QB of the Cleveland Browns, and will face the San Francisco 49ers. Colin Cowherd asks if Sanders is ready to be the starter for the Browns and if he can help them win games.

The San Francisco 49ers didn’t play great, but they managed to snag a win in a game they needed to have to keep their spot in the NFC playoff picture.