The 49ers (8-4) overcame three interceptions off Brock Purdy and posted a 20-9 victory over the Carolina Panthers (6-6).

Brock Purdy's three interceptions did little to stand in the way of another San Francisco 49ers victory as they took care of ...

Christian McCaffrey forced 11 missed tackles, closing in on a new career high as his running keeps the 49ers’ offense on ...

Devin Neal, Parker Washington and Trevor Lawrence are among UPI senior sports writer Alex Butler's fantasy football waiver ...

McCaffrey made history again in Monday’s game, prompting a big announcement from the NFL.

Christian McCaffrey galloped for 142 yards and the San Francisco 49ers defense allowed just 230 to power a primetime win over ...

The San Francisco 49ers overcame that Thanksgiving Week generosity and toppled the Carolina Panthers 20-9, thanks largely to ...

Christian McCaffrey enjoyed a big night after helping the San Francisco 49ers to a 20-9 victory over his former team, the ...

Christian McCaffrey didn't have any strong feelings about playing against his old team for the first time since the 2022 trade that sent him to the San Francisco 49ers.

"We do it all the time in practice, so it's not a big deal," Trent Williams said of McCaffrey's untouched TD. "But yeah, it's ...

The 49ers picked up a pivotal victory over the Panthers for its playoff hopes. A look at San Francisco's best performances vs ...

Christian McCaffrey had a big night in his first game against Carolina since the Panthers traded him to San Francisco three ...