Three first-half interceptions turned Purdy into a dink-and-dunker for the rest of the game. The 49ers need the good Purdy ...

Laura Rutledge is a pro's pro. The veteran ESPN host and reporter is one of the best in the business. The University of ...

McCaffrey made history again in Monday’s game, prompting a big announcement from the NFL.

Brock Purdy's three interceptions did little to stand in the way of another San Francisco 49ers victory as they took care of ...

San Francisco 49ers star running back Christian McCaffrey faced his former team for the first time since they traded him ...

Christian McCaffrey dominated his former Carolina Panthers team as the San Francisco 49ers secured a 20-9 victory on "Monday ...

With a win tonight, the 49ers’ odds of making the playoffs move from 83 percent from 89 percent in The Athletic’s NFL Playoff ...

Christian McCaffrey had a big night in his first game against Carolina since the Panthers traded him to San Francisco three ...

The San Francisco 49ers are back at Levi’s Stadium in Week 12 of the NFL season with a “Monday Night Football” matchup set ...

Is Christian McCaffrey the running back to target for Monday Night Football, or will Rico Dowdle stay hot in Week 12?

SportsLine's AI Model has simulated 49ers vs. Panthers on 'Monday Night Football' and revealed an NFL SGP that pays over 6-1 ...

Odds, game bets, prop plays and analysis to help you bet Monday night's Carolina Panthers-San Francisco 49ers game.