Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 20 (Oct. 1, 2002), pp. 13217-13221 (5 pages) Changes in hippocampal function seem critical for cognitive ...
Scientists observed that CREB activates specific genes based on the co-factor involved. Investigators at St. Jude Children’s Research Hospital discovered how a transcription factor called CREB ...
Mitogen-activated protein kinase (MAPK) and Wnt signaling pathways are critical for melanocyte development and melanogenesis and could be novel therapeutic targets for modulating melanin synthesis.
The molecular mechanisms behind the reorganization of synapses that leads to memory storage are the subject of a trio of studies published this week. In the lead story, Kimberly Maguschak and Kerry ...
NMDA receptors populate the synapse, where they participate in nerve signaling and promote cell survival pathways. But those same receptors, when they spread out into extrasynaptic regions, can ...
Cong Peng et al., at Department of Dermatology, Xiangya Hospital, Central South University, China, conducted a study titled "NETO2 promotes melanoma progression via activation of the Ca²⁺/CaMKII ...
Cystic fibrosis (CF) patients undergo progressive airway destruction caused in part by chronic neutrophilic inflammation. While opportunistic pathogens infecting CF airways can cause inflammation, we ...