Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

Even after Christian McCaffrey’s return to the field, the story surrounding his Achilles injury and the impact it’s having on ...

Christian McCaffrey has been inefficient in his three games played since dealing with Achilles tendinitis. He doesn't look ...

Speaking with reporters on Wednesday, San Francisco 49ers head coach Kyle Shanahan says it's "unfair" to expect running back ...

San Francisco 49ers running back Christian McCaffrey is three games into his return from injury. The two-time first-team ...

After fielding one of the best-rushing offenses in the NFL, with Jordan Mason leading the way and Isaac Guerendo rounding out ...

Olivia Culpo, former Miss Universe, has launched exclusive 49ers gear with Amazon in time for Cyber Monday. This announcement ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

The San Francisco 49ers face a critical clash against the Buffalo Bills this Sunday, and defensive end Leonard Floyd is ...

LB Fred Warner, WR Deebo Samuel Sr., RB Christian McCaffrey and DL Nick Bosa identified key areas for improvement as the team ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

Head coach Kyle Shanahan explains why the 49ers don't rotate their running backs to give Christian McCaffrey a breather.