Buffalo Bills face Denver Broncos Sat at 4:30 p.m. EST. Broncos are favored; total points set at 46.5. Donnie and Joe take a look at the current betting odds.

Many fans and pundits view the Bills as clear favorites against the Broncos. Steven A. Smith doesn't see it that way.

Last year, the Denver Broncos made the playoffs and faced the Buffalo Bills in the wildcard round. During that game, the Bills’ offense exposed a vital weakness of the defensive side of the ball for the Broncos.

The AFC Divisional Round of the playoffs open Saturday afternoon in Denver when Sean Payton and the Broncos take the field as a slight favorite against Josh Allen and the Buffalo Bills. For a time, the Bills were favored over the top seed in the AFC, but the line is back to where it opened with Bo Nix and co. favored by 1.5 points.

Jim Nantz (play-by-play) and Tony Romo (analyst) will call the game for CBS with Tracy Wolfson reporting from the sideline. On the radio, the game will be nationally broadcast on Sports USA and locally broadcast on KOA 850 AM & 94.1 FM.

The Denver Broncos are preparing for their divisional round against the Buffalo Bills. The most significant advantage for head coach Sean Payton's team is that they have a home-field advantage at Empower Field at Mile High,

The Bills and Broncos will face each other again with a trip to the AFC Championship on the line. Injuries and Josh Allen's excellence lead the keys to the game.

SportsLine's model has simulated Broncos vs. Bills 10,000 times and is going Over on the total, projecting 47 combined points. It also says one side of the spread hits in well over 50% of simulations. You can only get the pick at SportsLine.

USA Today's NFL experts make their picks for an NFL playoff showdown between the Denver Broncos and Buffalo Bills