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  1. Zofran Patient Tips: 7 things you should know - Drugs.com

    Apr 8, 2025 · Easy-to-read patient tips for Zofran covering how it works, benefits, risks, and best practices.

  2. Ondansetron (Zofran, Zofran ODT, Zuplenz): Uses, Side Effects ... - WebMD

    Jul 3, 2024 · Ondansetron blocks a specific receptor in the gut (intestines) and brain called 5-HT 3 that normally causes nausea and vomiting when your body is exposed to certain substances, …

  3. Zofran (Ondansetron): Uses, Interactions & Side Effects

    Zofran® (ondansetron) is a medication that prevents nausea and vomiting caused by chemotherapy, radiation or surgery. It blocks substances in your body that can cause nausea …

  4. Ondansetron: MedlinePlus Drug Information

    It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. How should this medicine be used? Ondansetron comes as a tablet, a rapidly …

  5. Ondansetron (oral route, oromucosal route) - Mayo Clinic

    Dec 1, 2025 · Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. It is also used to prevent nausea and vomiting …

  6. Zofran (Ondansetron) – Anti-Nausea Medication That Works Fast

    How does it work? Zofran blocks the action of serotonin — a chemical messenger that, when elevated by treatments like chemotherapy, sends powerful nausea signals to the brain. Think …

  7. How Does Zofran Work? | Zofran Uses - Healthgrades

    Feb 13, 2020 · It belongs to a class called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin. This disrupts nausea signals between the brain and gut. …

  8. What Does Zofran Do: Unlocking the Power of This Popular …

    May 29, 2025 · Zofran works by targeting the serotonin 5-HT3 receptors in the body. These receptors are found in the vomiting center of the brain and in the gastrointestinal tract. When …

  9. Ondansetron (Zofran): Uses, Side Effects, Dosage & More - GoodRx

    Mar 17, 2024 · Ondansetron (Zofran) is an antiemetic (or anti-nausea) medication. It's used to prevent nausea and vomiting after surgery or cancer treatments. It works by stopping a …

  10. How Ondansetron Works: A Guide to Use and Safety

    Dec 16, 2024 · Ondansetron (Zofran) was developed as an antiemetic (anti-vomiting) medication in the 1980s. It blocks a specific serotonin receptor called 5-HT3. It does this in two main …